Sr. Reliability Engineer

Company: Takeda
Location: Los Angeles
Posted on: July 10, 2025

Job Description:

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the Role: Under the direction of the LAFE Management Team and the Manager for Reliability Engineering, contribute to the reliability, design, development and enhancement of manufacturing and support equipment. You will be responsible for improving the reliability of manufacturing equipment, utilities, critical systems and maintenance processes by applying the principles of Reliability Centered Maintenance. Apply Root Cause Analysis methodologies to improve equipment that support manufacturing operations in a dynamic, fast-paced cGMP, biotechnology environment. Measure reliability performance and demonstrate success of improvements. Support capital projects as needed. May be assigned other duties. This position will provide technical support to the manufacturing and maintenance functions for the operation of the equipment and processes. Supervise and develop junior and senior staff. How you will contribute: Work with Los Angeles Fractionation Expansion (LAFE) Project Engineering Team (PET) to apply Reliability Centered Maintenance strategies to support installation, commissioning and validation of new equipment such as vessels, centrifuges, filter presses, Clean in Place skids, Heat Exchangers, AHU, Utilities, etc. Develop the maintenance strategy, plans, SOPs, parts lists, BOMs and frequencies for new and modified equipment for Los Angeles Fractionation Expansion (LAFE) Project. Perform the review, improvement and update of Maintenance SOPs, Parts Lists, BOMs and CMMS data integrity for existing equipment. Support CQV activities for LAFE. Participate in LAFE start up and ramp up activities. Perform data analysis of corrective work orders in CMMS to identify trends and area focus for improvements Perform functional equivalency assessment of spare parts. In collaboration with engineering, manufacturing, and maintenance personnel perform or support troubleshooting of equipment. Conducts or participates in Root Cause Failure Analysis (RCFA) and Failure Mode Effect Analysis (FMEA). Execute Reliability Centered Maintenance (RCM) improvement projects in assigned area. Participate and provide support for audits. Support the implementation of predictive maintenance across the facility May assists in the preparation of and/or participation in technical reviews of equipment design projects. May participate in FAT and commissioning of new or modified equipment Identify cost/waste/energy reduction opportunities May be assigned change control, Quality CAPA and Safety CAPA tasks Report project and operational metrics May perform other duties as assigned What you bring to Takeda: Required: Bachelor's degree in engineering discipline required. Chemical, Mechanical, Electrical Engineering Degree Preferred. 3 years of related experience. Mechanical/Electrical/Chemical specialty preferred. Familiarity with cGMPs is a plus Must have proficient computer skills and be experienced using MS Office software (Word, Excel and PowerPoint) and MS Project. Must possess knowledge of the core engineering principles: heat transfer, mass transfer, thermodynamics and fluid mechanics. Demonstrated strong mechanical aptitude and problem-solving skills required. Hands-on troubleshooting experience is required. Must have good interpersonal skills and be able to work effectively and efficiently in a team-based environment. Must be organized and detail focused. Familiarity with Biotechnology manufacturing operations such as purification, fractionation and their support systems such as CIP, SIP, HVAC, plant and clean utilities, is a plus. Knowledge of common biotechnology manufacturing equipment such as pumps, heat exchangers, tanks, mixers, valves, centrifuges, and filter presses is a plus. Familiarity with project management principles is a plus. Passion for Improving Lives: Must be able to put our patients at the center of everything we do. Quest for Innovation: Must be able to operate with agility and a learning mindset so that we can accelerate breakthrough innovations. Inspired Teams environment: Must be able to thrive in diverse high performing teams. Engaged with the World around Us: Must be able to embrace change and seek diverse perspectives and partnerships to benefit patients and make a positive impact on the world. The candidate must have good communication skills and the ability to perform effectively in multi-disciplinary teams Demonstrated success in delivering results in several technical challenges. Important Considerations: At Takeda, our patients rely on us to deliver quality products. As a result, we must follow strict rules in our manufacturing facilities to ensure we are not endangering the quality of the product. In this role, you may: Work in a controlled environment requiring special gowning and wear protective clothing over the head, face, hands, feet and body. This may include additional hearing protection for loud areas. Need to remove all make-up, jewelry, contact lenses, nail polish and/or artificial fingernails while in the manufacturing environment. Work in a cold, wet environment. Work multiple shifts, including weekends, or be asked to work supplemental hours, as necessary. Work around chemicals such as alcohol, acids, buffers and Celite that may require respiratory protection. May be required to work in a confined area. Some Clean Room and cool/hot storage conditions. Must be able to lift, push, pull and carry up to 25 lbs. In general, the position requires a combination of sedentary work and walking around observing conditions in the facility. More About Us: At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work. Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. GMSGQ ZR1 LI-MA1 Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: USA - CA - Los Angeles U.S. Base Salary Range: $86,500.00 - $135,960.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations USA - CA - Los Angeles Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes

Keywords: Takeda, Long Beach , Sr. Reliability Engineer, Engineering , Los Angeles, California