Senior Scientist I/II, Biologics Analytical R&D (Mass Spec)
Company: AbbVie
Location: Irvine
Posted on: July 10, 2025
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Job Description:
Company Description AbbVie's mission is to discover and deliver
innovative medicines and solutions that solve serious health issues
today and address the medical challenges of tomorrow. We strive to
have a remarkable impact on people's lives across several key
therapeutic areas immunology, oncology, neuroscience, and eye care
and products and services in our Allergan Aesthetics portfolio. For
more information about AbbVie, please visit us at www.abbvie.com .
Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and
Tik Tok . Job Description AbbVie Biologics Analytical Research &
Development (Biologics Analytical R&D) at Irvine is an
analytical sciences organization responsible for early-stage CMC
analytical activities related to the development of AbbVie's
neurotoxin and biologics products.Careers in AbbVie Biologics
Analytical R&D provide opportunities to work collaboratively
with cross-functional teams to drive scientific understanding and
innovative product development strategies.The biologics
characterization group develops analytical techniques for in-depth
characterization of biologics using mass spectrometry and other
analytical techniques. We are looking for candidates with strong
scientific experience to join the AbbVie Analytical R&D team
and can offer exciting career opportunities for these candidates.
Responsibilities: Execute the analysis and characterization of
neurotoxins and biopharmaceuticals. Create written procedures and
protocols. Mentor staff within a matrix environment when needed.
Apply routine and specialized analytical techniques to characterize
and quantify biopharmaceuticals. Maintain reagent supplies,
notebooks, summarize results in written reports and communicate
observations to ensure that the end user receives quality methods
in a timely manner. Comply with Quality Principals related to data
generation and reporting. Actively participate in cross-functional
teams within Biologics Development and provide support to external
departments. Openly share scientific expertise and collaboratively
help the team to formulate rational solutions to problems. Develop
protocols and SOPs, train staff and maintain the laboratory
consistent with departmental and company requirements. Understand,
document, and adjust Quality Systems to match the project stage
(e.g. pre-development or development). Independently plans
experimental work and execute protocols in support of biologics
process development, formulation development, and stability studies
as necessary. Independently generates, compiles, and evaluates data
for technical reports to support regulatory filings for new
biological products. Maintain a good and current knowledge of
scientific and technical literature pertinent to the project and
necessary for development of state-of-the-art analytical methods,
including the acquisition of necessary equipment. Keep up to date
on current and innovative developments in the biologics
characterization field. Make high quality scientific presentations
at internal management, regional and national meetings to help
advance Abbvies image as the thought and product leader in the
neuromodulator field. Adhere to polices to work in Biosafety level
2 laboratories in compliance with AbbVie internal and applicable
regulatory requirements. Consistently treats other team members and
all Abbvie employees with respect. Qualifications Qualifications
Senior Scientist I: Bachelors Degree or equivalent education and
typically, 10 years of experience, Masters Degree or equivalent
education and typically 8 years of experience, PhD and no necessary
experience. Senior Scientist II: Bachelors Degree or equivalent
education and typically, 12 years of experience, Masters Degree or
equivalent education and typically 10 years of experience, PhD and
typically 4 years of experience Extensive experience with the
application of mass spectrometric and separation techniques for the
characterization of proteins, their degradation and modification
products, and impurities. Experience in using data analysis
software such as BioPharma Finder or Protein Metrics Byos/Byonic
Experience in developing LC-MS Methods (peptide mapping, top-down,
PRM, DIA), routine operation, and maintenance of TOF and Orbitrap
mass spectrometers Understanding in CMC development strategy of
biologics drugs is expected. A solid understanding of methods and
procedures related to the production and characterization of
biopharmaceuticals in a regulated environment is expected. A strong
analytical and instrument skills and a thorough understanding and
working knowledge of analytical method development and validation.
Working knowledge of the requirements of working in a cGMP
environment is desired. Additional Information Applicable only to
applicants applying to a position in any location with pay
disclosure requirements under state or local law: Leveling will be
tied to experience. This is an on-site opportunity located in
Irvine, CA. This position works directly with neurotoxin and
biologics products. The compensation range described below is the
range of possible base pay compensation that the Company believes
ingood faith it will pay for this role at the time of this posting
based on the job grade for this position. Individualcompensation
paid within this range will depend on many factors including
geographic location, and we may ultimatelypay more or less than the
posted range. This range may be modified in the future. We offer a
comprehensive package of benefits including paid time off
(vacation, holidays, sick), medical/dental/visioninsurance and
401(k) to eligible employees. This job is eligible to participate
in our short-term incentive programs. Note: No amount of payis
considered to bewages or compensation until such amount is earned,
vested, and determinable.The amount and availability of any bonus,
commission, incentive, benefits, or any other form of compensation
and benefitsthat are allocable to a particular employee remains in
the Company's sole and absolute discretion unless and until paid
andmay be modified at the Companys sole and absolute discretion,
consistent with applicable law. AbbVie is an equal opportunity
employer and is committed to operating with integrity, driving
innovation, transforming lives and serving our community. Equal
Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to
learn more, visit
https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation,
click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Keywords: AbbVie, Long Beach , Senior Scientist I/II, Biologics Analytical R&D (Mass Spec), Science, Research & Development , Irvine, California